5JXH

Structure the proprotein convertase furin in complex with meta-guanidinomethyl-Phac-RVR-Amba at 2.0 Angstrom resolution.

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
AFurinpolymer48252388.61
UniProt (P09958)
Pfam (PF00082)
Pfam (PF01483)
Homo sapiens (Human)Dibasic-processing enzyme,Paired basic amino acid residue-cleaving enzyme,PACE
H2UC-ARG-VAL-ARG-00Spolymer5735.91
synthetic construct
CALCIUM IONnon-polymer40.13
SODIUM IONnon-polymer23.04
CHLORIDE IONnon-polymer35.51
waterwater18.0534

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains2
Total molecular weight53124.5
Non-Polymers*Number of molecules8
Total molecular weight247.6
All*Total molecular weight53372.2
*Water molecules are not included.