5JSQ

Trypanosome brucei Hypoxanthine-guanine phosphoribosyltranferase in complex with a 9-[7-(phosphonoheptyl]guanine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	hypoxanthine-guanine phosphoribosyltranferase	polymer	216	24221.8	2	UniProt (Q07010) Pfam (PF00156)	Trypanosoma brucei brucei	HGPRTase
2	C, I (A, B)	[6-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)hexyl]phosphonic acid	non-polymer		315.3	2	Chemie (6MS)
3	D, J (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
4	E, F, K (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	G, L (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	H, M (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
7	N, O (A, B)	water	water		18.0	401	Chemie (HOH)

Sequence modifications

A, B: 1 - 210 (UniProt: Q07010)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48443.6
Non-Polymers*	Number of molecules	11
	Total formula weight	1359.8
All*	Total formula weight	49803.3

*Water molecules are not included.