5JQ6
Crystal structure of ClfA in complex with the Fab fragment of Tefibazumab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Clumping factor A | polymer | 329 | 35801.5 | 1 | UniProt (G0XY13) Pfam (PF17961) Pfam (PF10425) UniProt (by SIFTS) (Q53653) | Staphylococcus aureus | |
| 2 | B (H) | Tefibazumab FAB FRAGMENT HEAVY CHAIN | polymer | 222 | 23737.8 | 1 | Mus musculus Homo sapiens | ||
| 3 | C (L) | Tefibazumab FAB FRAGMENT LIGHT CHAIN | polymer | 216 | 23756.4 | 1 | Mus musculus Homo sapiens | ||
| 4 | D, E, F (A, H, L) | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A: 229 - 545 (UniProt: G0XY13)
| PDB | External Database | Details |
|---|---|---|
| Met 217 | - | initiating methionine |
| Arg 218 | - | expression tag |
| Gly 219 | - | expression tag |
| Ser 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
| His 226 | - | expression tag |
| Gly 227 | - | expression tag |
| Ser 228 | - | expression tag |
| Cys 327 | Asp 327 | engineered mutation |
| Cys 541 | Lys 541 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 83295.6 | |
| All* | Total formula weight | 83295.6 |
