5JQ6

Crystal structure of ClfA in complex with the Fab fragment of Tefibazumab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Clumping factor A	polymer	329	35801.5	1	UniProt (G0XY13) Pfam (PF17961) Pfam (PF10425) UniProt (by SIFTS) (Q53653) In PDB	Staphylococcus aureus
2	H	Tefibazumab FAB FRAGMENT HEAVY CHAIN	polymer	222	23737.8	1		Mus musculus Homo sapiens
3	L	Tefibazumab FAB FRAGMENT LIGHT CHAIN	polymer	216	23756.4	1		Mus musculus Homo sapiens
4		water	water		18.0	205	Chemie (HOH)

Sequence modifications

A: 229 - 545 (UniProt: G0XY13)

PDB	External Database	Details
Met 217	-	initiating methionine
Arg 218	-	expression tag
Gly 219	-	expression tag
Ser 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
Gly 227	-	expression tag
Ser 228	-	expression tag
Cys 327	Asp 327	engineered mutation
Cys 541	Lys 541	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	83295.6
All*	Total formula weight	83295.6

*Water molecules are not included.