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5JPV

Efficient targeting of the asialoglycoprotein receptor by polyvalent display of a compact galactoseamine mimic

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Asialoglycoprotein receptor 1polymer14517011.62UniProt (P07306)
Pfam (PF00059)
Homo sapiens (Human)ASGPR 1,C-type lectin domain family 4 member H1,Hepatic lectin H1,HL-1
2C, D
(C, D)
beta-D-galactopyranose-(1-4)-alpha-D-glucopyranosebranched342.32In PDB
BIRD (PRD_900008)
GlyTouCan (G88362QR)
alpha-lactose
3E, F, G, I, J...
(A, B)
CALCIUM IONnon-polymer40.16Chemie (CA)
4H
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5L, M
(A, B)
waterwater18.0276Chemie (HOH)
Sequence modifications
A, B: 147 - 290 (UniProt: P07306)
PDBExternal DatabaseDetails
Met 146-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34023.1
BranchedNumber of molecules2
Total formula weight684.6
Non-Polymers*Number of molecules7
Total formula weight275.9
All*Total formula weight34983.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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