5JPV
Efficient targeting of the asialoglycoprotein receptor by polyvalent display of a compact galactoseamine mimic
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Asialoglycoprotein receptor 1 | polymer | 145 | 17011.6 | 2 | UniProt (P07306) Pfam (PF00059) | Homo sapiens (Human) | ASGPR 1,C-type lectin domain family 4 member H1,Hepatic lectin H1,HL-1 |
2 | C, D (C, D) | beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 2 | In PDB BIRD (PRD_900008) GlyTouCan (G88362QR) | alpha-lactose | ||
3 | E, F, G, I, J... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
4 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | L, M (A, B) | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence modifications
A, B: 147 - 290 (UniProt: P07306)
PDB | External Database | Details |
---|---|---|
Met 146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34023.1 | |
Branched | Number of molecules | 2 |
Total formula weight | 684.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 275.9 | |
All* | Total formula weight | 34983.7 |