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5JNC

Crystal structure for the complex of human carbonic anhydrase IV and 4-aminomethylbenzene sulfonamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Carbonic anhydrase 4polymer26630364.54UniProt (P22748)
Pfam (PF00194)
Homo sapiens (Human)Carbonate dehydratase IV,Carbonic anhydrase IV,CA-IV
2E, L, R, Y
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
3F, M, S, Z
(A, B, C, D)
4-(aminomethyl)benzene-1-sulfonamidenon-polymer186.24Chemie (6LH)
4AA, BA, G, H, N...
(D, A, B, C)
SULFATE IONnon-polymer96.18Chemie (SO4)
5CA, I, P, V
(D, A, B, C)
ACETATE IONnon-polymer59.04Chemie (ACT)
6J, K, Q, W, X
(A, B, C)
GLYCEROLnon-polymer92.15Chemie (GOL)
7DA, EA, FA, GA
(A, B, C, D)
waterwater18.0937Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight121457.9
Non-Polymers*Number of molecules25
Total formula weight2471.7
All*Total formula weight123929.6
*Water molecules are not included.

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PDB entries from 2025-12-03

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