5JNA
Crystal structure for the complex of human carbonic anhydrase IV and topiramate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Carbonic anhydrase 4 | polymer | 266 | 30364.5 | 4 | UniProt (P22748) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase IV,Carbonic anhydrase IV,CA-IV |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | A, B, C, D | [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate | non-polymer | 339.4 | 4 | Chemie (TOR) | |||
| 4 | A, B, C, D | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 5 | A, B, C | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | B, C, D | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 7 | water | water | 18.0 | 888 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 121457.9 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2841.0 | |
| All* | Total formula weight | 124298.9 |
