5JNA
Crystal structure for the complex of human carbonic anhydrase IV and topiramate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 4 | polymer | 266 | 30364.5 | 4 | UniProt (P22748) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase IV,Carbonic anhydrase IV,CA-IV |
| 2 | E, J, P, V (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, K, Q, W (A, B, C, D) | [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate | non-polymer | 339.4 | 4 | Chemie (TOR) PubChem (16757856) PubChem (5514) PubChem (21252335) PubChem (40467244) PubChem (40467245) PubChem (40467246) PubChem (45357229) PubChem (56840897) PubChem (44309678) PubChem (58649031) PubChem (60060464) PubChem (71296901) PubChem (73265248) PubChem (5284627) PubChem (92144467) PubChem (92779111) PubChem (6850784) PubChem (97406011) PubChem (10664802) PubChem (124425856) PubChem (124436525) PubChem (13458469) | |||
| 4 | G, H, L, M, R... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 5 | I, O, U (A, B, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 6 | N, T, Z (B, C, D) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) PubChem (175) | |||
| 7 | AA, BA, CA, DA (A, B, C, D) | water | water | 18.0 | 888 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 121457.9 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2841.0 | |
| All* | Total formula weight | 124298.9 |
