5JN5

Crystal structure of the D263Y missense variant of human PGM1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphoglucomutase-1	polymer	585	64319.8	2	UniProt (P36871) Pfam (PF02878) Pfam (PF02879) Pfam (PF02880) In PDB	Homo sapiens (Human)	PGM 1,Glucose phosphomutase 1
2	A, B	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
3	A, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4		water	water		18.0	1423	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: P36871)

PDB	External Database	Details
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag
Tyr 263	Asp 263	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128639.6
Non-Polymers*	Number of molecules	9
	Total formula weight	752.6
All*	Total formula weight	129392.2

*Water molecules are not included.