5JLH
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Actin, cytoplasmic 2 | polymer | 374 | 41707.6 | 5 | UniProt (P63261) Pfam (PF00022) In PDB | Homo sapiens (Human) | Gamma-actin |
| 2 | F, G | Myosin-14,Alpha-actinin A | polymer | 1039 | 117570.6 | 2 | UniProt (Q7Z406) UniProt (P05095) Pfam (PF02736) Pfam (PF00063) Pfam (PF00435) In PDB | Homo sapiens (Human) | Myosin heavy chain 14,Myosin heavy chain,non-muscle IIc,Non-muscle myosin heavy chain IIc,NMHC II-C, ALPHA-ACTININ,Actin-binding protein A,F-actin cross-linking protein |
| 3 | H, I, J, K | Tropomyosin alpha-3 chain | polymer | 135 | 11507.2 | 4 | Homo sapiens (Human) | ||
| 4 | A, B, C, D, E | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 5 | Chemie (ADP) | |||
| 5 | A, B, C, D, E | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) |
Sequence modifications
F, G: 1 - 799 (UniProt: Q7Z406)
F, G: 802 - 1039 (UniProt: P05095)
| PDB | External Database | Details |
|---|---|---|
| Ala 800 | - | linker |
| Ser 801 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 489707.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2257.5 | |
| All* | Total formula weight | 491965.4 |
