5JKE
Crystal structure of human IZUMO1-JUNO complex (crystal form 3)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Izumo sperm-egg fusion protein 1 | polymer | 246 | 28163.3 | 2 | UniProt (Q8IYV9) Pfam (PF15005) Pfam (PF16706) In PDB | Homo sapiens (Human) | Oocyte binding/fusion factor,OBF,Sperm-specific protein izumo |
2 | B, D | Sperm-egg fusion protein Juno | polymer | 221 | 25428.8 | 2 | UniProt (A6ND01) Pfam (PF03024) In PDB | Homo sapiens (Human) | Folate receptor 4,Folate receptor delta,FR-delta,IZUMO1 receptor protein JUNO |
3 | A, B, C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
4 | A, D | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
5 | B, D | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, C: 22 - 255 (UniProt: Q8IYV9)
B, D: 20 - 228 (UniProt: A6ND01)
PDB | External Database | Details |
---|---|---|
Arg 18 | - | expression tag |
Ser 19 | - | expression tag |
Pro 20 | - | expression tag |
Trp 21 | - | expression tag |
Glu 256 | - | expression tag |
Phe 257 | - | expression tag |
Leu 258 | - | expression tag |
Glu 259 | - | expression tag |
Val 260 | - | expression tag |
Leu 261 | - | expression tag |
Phe 262 | - | expression tag |
Gln 263 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Arg 16 | - | expression tag |
Ser 17 | - | expression tag |
Pro 18 | - | expression tag |
Trp 19 | - | expression tag |
Glu 229 | - | expression tag |
Phe 230 | - | expression tag |
Leu 231 | - | expression tag |
Glu 232 | - | expression tag |
Val 233 | - | expression tag |
Leu 234 | - | expression tag |
Phe 235 | - | expression tag |
Gln 236 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 107184.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1147.9 | |
All* | Total formula weight | 108332.2 |