5JK7

The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA damage-binding protein 1	polymer	1140	127097.5	2	UniProt (Q16531) Pfam (PF10433) Pfam (PF03178)	Homo sapiens (Human)	DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe
2	C, E (C, E)	Protein VPRBP	polymer	361	41178.2	2	UniProt (Q9Y4B6)	Homo sapiens (Human)	DDB1- and CUL4-associated factor 1,HIV-1 Vpr-binding protein,VprBP,Serine/threonine-protein kinase VPRBP,Vpr-interacting protein
3	D, G (D, G)	Uracil-DNA glycosylase	polymer	222	25383.0	2	UniProt (P13051) Pfam (PF03167)	Homo sapiens (Human)	UDG
4	F, H (F, H)	Protein Vpr	polymer	96	11396.9	2	UniProt (P12520) Pfam (PF00522)	Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1)	R ORF protein,Viral protein R

Sequence modifications

C, E: 1045 - 1396 (UniProt: Q9Y4B6)

PDB	External Database	Details
Ala 1044	-	expression tag
Leu 1397	-	expression tag
Glu 1398	-	expression tag
His 1399	-	expression tag
His 1400	-	expression tag
His 1401	-	expression tag
His 1402	-	expression tag
His 1403	-	expression tag
His 1404	-	expression tag

D, G: 85 - 304 (UniProt: P13051)

PDB	External Database	Details
Val 83	-	expression tag
Phe 84	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	410111.1
All*	Total formula weight	410111.1

*Water molecules are not included.