5JJR
Dengue 3 NS5 protein with compound 29
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein | polymer | 892 | 102830.6 | 1 | UniProt (Q6DLV0) Pfam (PF01728) Pfam (PF00972) Pfam (PF20483) UniProt (by SIFTS) (Q6YMS4) | Dengue virus 3 | |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | E (A) | 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-4-methoxy-2-methyl-N-[(quinolin-8-yl)sulfonyl]benzamide | non-polymer | 492.6 | 1 | Chemie (68E) | |||
| 5 | F, H, J, L, M... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | I, K, O (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 8 | P (A) | water | water | 18.0 | 475 | Chemie (HOH) |
Sequence modifications
A: 4 - 895 (UniProt: Q6DLV0)
| PDB | External Database | Details |
|---|---|---|
| Met 5 | Gln 2495 | engineered mutation |
| Ile 72 | Val 2562 | engineered mutation |
| Glu 374 | Gly 2864 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 102830.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1722.9 | |
| All* | Total formula weight | 104553.5 |
