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5JJ0

Structure of G9a SET-domain with Histone H3K9M peptide and excess SAH

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BHistone-lysine N-methyltransferase EHMT2polymer27431661.92UniProt (Q96KQ7)
Pfam (PF05033)
Pfam (PF00856)
In PDB
Homo sapiens (Human)Euchromatic histone-lysine N-methyltransferase 2,HLA-B-associated transcript 8,Histone H3-K9 methyltransferase 3,H3-K9-HMTase 3,Lysine N-methyltransferase 1C,Protein G9a
2F, GHistone H3K9M mutant peptidepolymer111139.32UniProt (by SIFTS) (P68431)
In PDB
Homo sapiens
3A, BZINC IONnon-polymer65.48Chemie (ZN)
4A, BS-ADENOSYLMETHIONINEnon-polymer398.42Chemie (SAM)
5waterwater18.0130Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight65602.4
Non-Polymers*Number of molecules10
Total formula weight1320.1
All*Total formula weight66922.5
*Water molecules are not included.

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PDB entries from 2024-04-24

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