5JI8

Crystal structure of the BRD9 bromodomain and hit 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Bromodomain-containing protein 9	polymer	111	13057.2	1	UniProt (Q9H8M2) Pfam (PF00439)	Homo sapiens (Human)	Rhabdomyosarcoma antigen MU-RMS-40.8
2	B (A)	2-amino-1,3-benzothiazole-6-carboxamide	non-polymer		193.2	1	Chemie (6KT)
3	C (A)	water	water		18.0	156	Chemie (HOH)

Sequence modifications

A: 137 - 239 (UniProt: Q9H8M2)

PDB	External Database	Details
Leu 240	-	expression tag
Glu 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	13057.2
Non-Polymers*	Number of molecules	1
	Total formula weight	193.2
All*	Total formula weight	13250.4

*Water molecules are not included.