5JGD
Crystal structure of human TAK1/TAB1 fusion protein in complex with ligand 12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TAK1 kinase - TAB1 chimera fusion protein | polymer | 315 | 35531.0 | 1 | UniProt (O43318) UniProt (Q15750) Pfam (PF07714) In PDB | Homo sapiens (Human) | |
| 2 | A | N-(2-isopropoxy-3-(4-methylpiperazine-1-carbonyl)phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide | non-polymer | 455.5 | 1 | Chemie (6KD) | |||
| 3 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 31 - 303 (UniProt: O43318)
A: 468 - 504 (UniProt: Q15750)
| PDB | External Database | Details |
|---|---|---|
| Gly 26 | - | expression tag |
| Pro 27 | - | expression tag |
| Leu 28 | - | expression tag |
| His 29 | - | expression tag |
| Met 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35531.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 455.5 | |
| All* | Total formula weight | 35986.5 |
