5JG6
APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Anaphase-promoting complex subunit 11 | polymer | 70 | 8050.4 | 2 | UniProt (Q9NYG5) Pfam (PF12861) | Homo sapiens (Human) | APC11,Cyclosome subunit 11,Hepatocellular carcinoma-associated RING finger protein |
| 2 | B, C (B, C) | Polyubiquitin-B | polymer | 84 | 9255.8 | 2 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) | |
| 3 | E, F, G, H, I... (A, D) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A, D: 17 - 84 (UniProt: Q9NYG5)
B, C: 0 - 78 (UniProt: P0CG47)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | expression tag |
| Ser 16 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Leu 4 | Phe 80 | conflict |
| Pro 8 | Leu 84 | conflict |
| Arg 9 | Thr 85 | conflict |
| Ile 42 | Arg 118 | conflict |
| Phe 44 | Ile 120 | conflict |
| Val 47 | Gly 123 | conflict |
| Arg 49 | Gln 125 | conflict |
| Lys 64 | Glu 140 | conflict |
| Ser 66 | Thr 142 | conflict |
| Leu 68 | His 144 | conflict |
| Ala 70 | Val 146 | conflict |
| Met 71 | Leu 147 | conflict |
| Val 73 | Leu 149 | conflict |
| Pro 74 | Arg 150 | conflict |
| Lys 76 | Gly 152 | conflict |
| Lys 78 | Gln 154 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 34612.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 35004.7 |
