5JA4
Crystal structure of human TONSL and MCM2 HBDs binding to a histone H3-H4 tetramer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone H3.3 | polymer | 79 | 9026.5 | 1 | UniProt (P84243) Pfam (PF00125) | Homo sapiens (Human) | |
| 2 | B (B) | Histone H4 | polymer | 102 | 11263.2 | 1 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (Human) | |
| 3 | C (C) | DNA replication licensing factor MCM2 | polymer | 70 | 7860.4 | 1 | UniProt (P49736) Pfam (PF12619) | Homo sapiens (Human) | Minichromosome maintenance protein 2 homolog,Nuclear protein BM28 |
| 4 | D (D) | Tonsoku-like protein | polymer | 181 | 20368.0 | 1 | UniProt (Q96HA7) Pfam (PF00023) | Homo sapiens (Human) | Inhibitor of kappa B-related protein,IkappaBR,NF-kappa-B inhibitor-like protein 2,Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 |
| 5 | E (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 6 | F, G (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 48518.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 379.4 | |
| All* | Total formula weight | 48897.5 |
