5J9W

Crystal structure of the NuA4 core complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I (E, A, I)	Histone acetyltransferase ESA1	polymer	305	36556.9	3	UniProt (Q08649) Pfam (PF17772) Pfam (PF01853)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
2	B, F, J (F, B, J)	Chromatin modification-related protein EAF6	polymer	113	12915.7	3	UniProt (P47128) Pfam (PF09340)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ESA1-associated factor 6
3	C, G, K (G, C, K)	Enhancer of polycomb-like protein 1	polymer	280	33320.5	3	UniProt (P43572) Pfam (PF10513)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
4	D, H, L (H, D, L)	Chromatin modification-related protein YNG2	polymer	120	13828.9	3	UniProt (P38806) Pfam (PF12998)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	ESA1-associated factor 4,ING1 homolog 2
5	M, N (E, I)	ACETYL COENZYME *A	non-polymer		809.6	2	Chemie (ACO) PubChem (25210474) PubChem (24860528) PubChem (53393727) PubChem (56846401) PubChem (44141873) PubChem (45254004) PubChem (444493) PubChem (53245716) PubChem (87656764) PubChem (181) PubChem (6302) PubChem (87656765) PubChem (89102998) PubChem (91746285) PubChem (6857822) PubChem (6917106) PubChem (134956084) PubChem (10079099) PubChem (124511019) PubChem (11987898) PubChem (16061174) PubChem (124931617) PubChem (129274027) PubChem (154496096) PubChem (162968672) PubChem (170108977)

Sequence modifications

E, A, I: 141 - 445 (UniProt: Q08649)

PDB	External Database	Details
Gln 338	Glu 338	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	289866.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1619.1
All*	Total formula weight	291485.2

*Water molecules are not included.