5J7F
Structure of MDM2 with low molecular weight inhibitor with aliphatic linker.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | E3 ubiquitin-protein ligase Mdm2 | polymer | 125 | 14159.2 | 4 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (Human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,p53-binding protein Mdm2 |
| 2 | E, F, G, H (A, B, C, D) | 4-({6-[(6-chloro-3-{1-[(4-chlorophenyl)methyl]-4-(4-fluorophenyl)-1H-imidazol-5-yl}-1H-indole-2-carbonyl)oxy]hexyl}amino)-4-oxobutanoic acid | non-polymer | 679.6 | 4 | Chemie (6GG) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56636.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2718.3 | |
| All* | Total formula weight | 59355.0 |
