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5J5Y

Translation initiation factor 4E in complex with m2(7,2'O)GppCCl2ppG mRNA 5' cap analog

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Eukaryotic translation initiation factor 4Epolymer19022145.14UniProt (P63073)
Pfam (PF01652)
Mus musculus (Mouse)mRNA cap-binding protein,eIF-4F 25 kDa subunit
2E, F
(A, B)
2-amino-9-{5-O-[(R)-{[(S)-{dichloro[(R)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2-O-methyl-beta-D-ribofuranosyl}-7-methyl-9H-purin-7-ium-6-olatenon-polymer698.12Chemie (6G6)
3G
(B)
GLYCEROLnon-polymer92.11Chemie (GOL)
4H, I, J, K
(A, B, C, D)
waterwater18.0269Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight88580.5
Non-Polymers*Number of molecules3
Total formula weight1488.4
All*Total formula weight90068.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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