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5J5X

Complex of PKA with the bisubstrate protein kinase inhibitor ARC-1416

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cAMP-dependent protein kinase catalytic subunit alphapolymer35140808.61UniProt (P17612)
Pfam (PF00069)
Homo sapiens (Human)PKA C-alpha
2B
(B)
47P-AZ1-DAL-DAR-DAR-DAR-DARpolymer81057.31Homo sapiens
3C, D, E
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
4F
(A)
4-(piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidinenon-polymer203.21Chemie (6J9)
5G, H
(A, B)
waterwater18.026Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight41865.9
Non-Polymers*Number of molecules4
Total formula weight491.4
All*Total formula weight42357.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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