5J5P

AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA topoisomerase 4 subunit B	polymer	409	45032.5	2	UniProt (Q59961) Pfam (PF02518) Pfam (PF00204)	Streptococcus pneumoniae	Topoisomerase IV subunit B
2	C, D, E, F (C, D, E, F)	DNA (5'-D(*GP*CP*GP*CP*GP*C)-3')	polymer	6	1810.2	4		synthetic construct
3	G, K (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
4	H, L (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	I, J, M, N (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	O, P, Q, R, S... (A, B, C, D, E...)	water	water		18.0	824	Chemie (HOH)

Sequence modifications

A, B: 1 - 402 (UniProt: Q59961)

PDB	External Database	Details
Ala 0	-	expression tag
Asp 217	Asn 217	conflict
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	97305.7
Non-Polymers*	Number of molecules	8
	Total formula weight	1155.6
All*	Total formula weight	98461.3

*Water molecules are not included.