5J3D

Crystal structure of human Fab 14N4 in complex with post-fusion RSV F

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, H (A, C, H)	14N4 heavy chain	polymer	224	23597.5	3		Homo sapiens (human)
2	B, D, L (B, D, L)	14N4 light chain	polymer	218	24001.5	3		Homo sapiens (human)
3	E, G, J (E, G, J)	Fusion glycoprotein F0	polymer	73	8301.5	3	UniProt (P03420)	Human respiratory syncytial virus A	Protein F
4	F, I, K (F, I, K)	Fusion glycoprotein F0	polymer	394	43782.8	3	UniProt (P03420) Pfam (PF00523)	Human respiratory syncytial virus A	Protein F

Sequence modifications

F, I, K: 147 - 513 (UniProt: P03420)

PDB	External Database	Details
Val 379	Ile 379	conflict
Val 447	Met 447	conflict
Gly 514	-	expression tag
Leu 515	-	expression tag
Glu 516	-	expression tag
Val 517	-	expression tag
Leu 518	-	expression tag
Phe 519	-	expression tag
Gln 520	-	expression tag
Gly 521	-	expression tag
Pro 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag
His 526	-	expression tag
His 527	-	expression tag
His 528	-	expression tag
His 529	-	expression tag
His 530	-	expression tag
Ser 531	-	expression tag
Ala 532	-	expression tag
Trp 533	-	expression tag
Ser 534	-	expression tag
His 535	-	expression tag
Pro 536	-	expression tag
Gln 537	-	expression tag
Phe 538	-	expression tag
Glu 539	-	expression tag
Lys 540	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	299049.7
All*	Total formula weight	299049.7

*Water molecules are not included.