5J39

Crystal Structure of the extended TUDOR domain from TDRD2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tudor and KH domain-containing protein	polymer	208	23631.3	2	UniProt (Q9Y2W6) Pfam (PF00567)	Homo sapiens (Human)	Tudor domain-containing protein 2
2	C, K (A, B)	CACODYLATE ION	non-polymer		137.0	2	Chemie (CAC)
3	D, E, F, G, H... (A, B)	UNKNOWN ATOM OR ION	non-polymer			18	Chemie (UNX)
4	W, X (A, B)	water	water		18.0	83	Chemie (HOH)

Sequence modifications

A, B: 309 - 498 (UniProt: Q9Y2W6)

PDB	External Database	Details
Met 291	-	initiating methionine
His 292	-	expression tag
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
Ser 298	-	expression tag
Ser 299	-	expression tag
Gly 300	-	expression tag
Arg 301	-	expression tag
Glu 302	-	expression tag
Asn 303	-	expression tag
Leu 304	-	expression tag
Tyr 305	-	expression tag
Phe 306	-	expression tag
Gln 307	-	expression tag
Gly 308	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47262.7
Non-Polymers*	Number of molecules	20
	Total formula weight	274.0
All*	Total formula weight	47536.6

*Water molecules are not included.