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5J2I

Ternary complex crystal structure of DNA polymerase Beta with T:C mismatch at the primer terminus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
Template Strandpolymer164828.11synthetic construct
3C
(P)
Primer Strandpolymer103061.01synthetic construct
4D
(D)
Downstream Primer Strandpolymer51536.01synthetic construct
5E
(A)
2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATEnon-polymer467.21Chemie (DUP)
6F, G
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7H, I
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
8J, K, L, M
(A, T, P, D)
waterwater18.0234Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47666.9
Non-Polymers*Number of molecules5
Total formula weight561.7
All*Total formula weight48228.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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