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5J2A

Ternary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
Template Strandpolymer164837.21synthetic construct
3C
(P)
Primer Strandpolymer103061.01synthetic construct
4D
(D)
Downstream Primer Strandpolymer51536.01synthetic construct
5E
(A)
2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATEnon-polymer467.21Chemie (DUP)
6F, G
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
7H, K
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
8I, J
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
9L, M, N, O
(A, T, P, D)
waterwater18.0257Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47675.9
Non-Polymers*Number of molecules7
Total formula weight632.7
All*Total formula weight48308.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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