5J19
phospho-Pon binding-induced Plk1 dimerization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PLK1 | polymer | 234 | 26929.7 | 2 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (Human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | C, D (C, D) | Phosphorylated peptide from Partner of Numb | polymer | 15 | 1699.8 | 2 | UniProt (O96561) | Drosophila melanogaster | PON |
| 3 | E, F, G (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A, B: 367 - 594 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 361 | - | expression tag |
| Pro 362 | - | expression tag |
| Gly 363 | - | expression tag |
| Ser 364 | - | expression tag |
| Glu 365 | - | expression tag |
| Phe 366 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57258.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 57535.2 |
