5J0D
Crystal structure of the bromodomain of human CREBBP in complex with a benzoxazepine compound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CREB-binding protein | polymer | 119 | 14223.3 | 1 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (Human) | |
2 | A | 7-(3,5-dimethoxyphenyl)-N-[(3S)-1-methylpiperidin-3-yl]-4-propanoyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide | non-polymer | 481.6 | 1 | Chemie (6F9) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
4 | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A: 1081 - 1197 (UniProt: Q92793)
PDB | External Database | Details |
---|---|---|
Ser 1079 | - | expression tag |
Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 14223.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 667.8 | |
All* | Total formula weight | 14891.1 |