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5IY5

Electron transfer complex of cytochrome c and cytochrome c oxidase at 2.0 angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, N
(A, N)
Cytochrome c oxidase subunit 1polymer51457093.92UniProt (P00396)
Pfam (PF00115)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide I
2B, O
(B, O)
Cytochrome c oxidase subunit 2polymer22726068.42UniProt (P68530)
Pfam (PF02790)
Pfam (PF00116)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide II
3C, P
(C, P)
Cytochrome c oxidase subunit 3polymer25929725.32UniProt (P00415)
Pfam (PF00510)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide III
4D, Q
(D, Q)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrialpolymer14416913.42UniProt (P00423)
Pfam (PF02936)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit IV isoform 1,COX IV-1
5E, R
(E, R)
Cytochrome c oxidase subunit 5A, mitochondrialpolymer10512083.72UniProt (P00426)
Pfam (PF02284)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide Va
6F, S
(F, S)
Cytochrome c oxidase subunit 5B, mitochondrialpolymer9810684.02UniProt (P00428)
Pfam (PF01215)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide VIa,Cytochrome c oxidase polypeptide Vb
7G, T
(G, T)
Cytochrome c oxidase subunit 6A2, mitochondrialpolymer849532.72UniProt (P07471)
Pfam (PF02046)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide VIa-heart,COXVIAH,Cytochrome c oxidase polypeptide VIb
8H, U
(H, U)
Cytochrome c oxidase subunit 6B1polymer799411.62UniProt (P00429)
Pfam (PF02297)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide VII,Cytochrome c oxidase subunit AED,Cytochrome c oxidase subunit VIb isoform 1,COX VIb-1
9I, V
(I, V)
Cytochrome c oxidase subunit 6Cpolymer738537.02UniProt (P04038)
Pfam (PF02937)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide VIc,Cytochrome c oxidase subunit STA
10J, W
(J, W)
Cytochrome c oxidase subunit 7A1, mitochondrialpolymer586553.52UniProt (P07470)
Pfam (PF02238)
Bos taurus (Bovine)Cytochrome c oxidase subunit VIIIc,VIIIC,Cytochrome c oxidase subunit VIIa-heart,Cytochrome c oxidase subunit VIIa-H,Cytochrome c oxidase subunit VIIa-muscle,Cytochrome c oxidase subunit VIIa-M
11K, X
(K, X)
Cytochrome c oxidase subunit 7B, mitochondrialpolymer495442.22UniProt (P13183)
Pfam (PF05392)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide VIIb,IHQ
12L, Y
(L, Y)
Cytochrome c oxidase subunit 7C, mitochondrialpolymer465362.32UniProt (P00430)
Pfam (PF02935)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide VIIIA,Cytochrome c oxidase polypeptide VIIc
13M, Z
(M, Z)
Cytochrome c oxidase subunit 8B, mitochondrialpolymer434738.52UniProt (P10175)
Pfam (PF02285)
Bos taurus (Bovine)Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8H,IX,VIIIb
14AA, BA
(1, 2)
Cytochrome cpolymer10511751.62UniProt (P00004)
Pfam (PF00034)
Equus caballus (Horse)
15CA, NB
(A, N)
COPPER (II) IONnon-polymer63.52Chemie (CU)
16DA, OB
(A, N)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
17CC, EA, OA, PB
(P, A, C, N)
SODIUM IONnon-polymer23.04Chemie (NA)
18FA, GA, QB, RB
(A, N)
HEME-Anon-polymer852.84Chemie (HEA)
19HA, SB
(A, N)
PEROXIDE IONnon-polymer32.02Chemie (PER)
20EC, FC, IA, JA, QA...
(P, A, C, N)
(1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATEnon-polymer749.07Chemie (PGV)
21JB, KA, LC, TB, YA
(L, B, Q, N, D)
TRISTEAROYLGLYCEROLnon-polymer891.55Chemie (TGL)
22AC, LA
(O, B)
DINUCLEAR COPPER IONnon-polymer127.12Chemie (CUA)
23AB, CB, FB, GB, MA...
(E, F, G, I, B...)
1,2-ETHANEDIOLnon-polymer62.19Chemie (EDO)
24BC, EB, HB, HC, NA...
(P, G, J, C, T...)
CHOLIC ACIDnon-polymer408.68Chemie (CHD)
25DC, PA
(P, C)
(1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATEnon-polymer768.12Chemie (PEK)
26DB, GC, OC, SA
(G, P, T, C)
CARDIOLIPINnon-polymer1464.04Chemie (CDL)
27IB, IC, JC, KB, KC...
(J, P, L, N, T...)
UNKNOWN LIGANDnon-polymer15Chemie (UNL)
28RC, ZA
(V, E)
(7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDEnon-polymer759.12Chemie (PSC)
29BB, MC
(F, S)
ZINC IONnon-polymer65.42Chemie (ZN)
30LB, VC
(M, Z)
DECYL-BETA-D-MALTOPYRANOSIDEnon-polymer482.62Chemie (DMU)
31WC, XC
(1, 2)
HEME Cnon-polymer618.52Chemie (HEC)
32AD, BD, CD, DD, ED...
(C, D, E, F, G...)
waterwater18.02237Chemie (HOH)
Sequence modifications
1, 2: 1 - 104 (UniProt: P00004)
PDBExternal DatabaseDetails
Ace 0-acetylation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains28
Total formula weight427796.4
Non-Polymers*Number of molecules74
Total formula weight28768.2
All*Total formula weight456564.6
*Water molecules are not included.

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PDB entries from 2025-12-10

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