5IWL
CD47-diabody complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (B, A) | 5F9 diabody | polymer | 234 | 25510.4 | 2 | Homo sapiens (Human) | ||
2 | C, D (C, D) | Leukocyte surface antigen CD47 | polymer | 114 | 12858.5 | 2 | UniProt (Q08722) Pfam (PF08204) | Homo sapiens (Human) | Antigenic surface determinant protein OA3,Integrin-associated protein,IAP,Protein MER6 |
3 | E, F, G, I, J... (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
4 | H, L (C, D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
5 | M, N, O (B, A, D) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
C, D: 1 - 114 (UniProt: Q08722)
PDB | External Database | Details |
---|---|---|
Asp 11 | Glu 29 | conflict |
Gly 15 | Cys 33 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 76737.7 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1627.6 | |
All* | Total formula weight | 78365.3 |