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5IVW

Human core TFIIH bound to DNA within the PIC

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1VTFIIH basal transcription factor complex helicase XPB subunitpolymer78289404.71UniProt (P19447)
Pfam (PF13625)
Pfam (PF04851)
Pfam (PF16203)
In PDB
Homo sapiens (Human)Basic transcription factor 2 89 kDa subunit, BTF2 p89, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, TFIIH basal transcription factor complex 89 kDa subunit, TFIIH p89, Xeroderma pigmentosum group B-complementing protein
2WTFIIH basal transcription factor complex helicase XPD subunitpolymer76087021.11UniProt (P18074)
Pfam (PF06733)
Pfam (PF06777)
Pfam (PF13307)
In PDB
Homo sapiens (Human)Basic transcription factor 2 80 kDa subunit, BTF2 p80, CXPD, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex 80 kDa subunit, TFIIH p80, Xeroderma pigmentosum group D-complementing protein
30General transcription factor IIH subunit 2polymer39544482.01UniProt (Q13888)
Pfam (PF04056)
Pfam (PF07975)
In PDB
Homo sapiens (Human)Basic transcription factor 2 44 kDa subunit, BTF2 p44, General transcription factor IIH polypeptide 2, TFIIH basal transcription factor complex p44 subunit
41General transcription factor IIH subunit 5polymer718060.41UniProt (Q6ZYL4)
Pfam (PF06331)
In PDB
Homo sapiens (Human)General transcription factor IIH polypeptide 5, TFB5 ortholog, TFIIH basal transcription factor complex TTD-A subunit
52General transcription factor IIH subunit 4polymer46252245.21UniProt (Q92759)
Pfam (PF03849)
Pfam (PF18307)
In PDB
Homo sapiens (Human)Basic transcription factor 2 52 kDa subunit, BTF2 p52, General transcription factor IIH polypeptide 4, TFIIH basal transcription factor complex p52 subunit
63General transcription factor IIH subunit 3polymer30834416.01UniProt (Q13889)
Pfam (PF03850)
In PDB
Homo sapiens (Human)p34, Basic transcription factor 2 44 kDa subunit, BTF2 p44, General transcription factor IIH polypeptide 2, TFIIH basal transcription factor complex p44 subunit
7Xscp-Xpolymer195879.91Homo sapiens
8Yscp-Ypolymer206071.91Homo sapiens
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight327581.1
All*Total formula weight327581.1
*Water molecules are not included.

221716

PDB entries from 2024-06-26

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