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5IVB

A High Resolution Structure of a Linked KDM5A Jmj Domain with Alpha-Ketoglutarate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ALysine-specific demethylase 5A,Lysine-specific demethylase 5Apolymer33037944.81UniProt (P29375)
Pfam (PF02375)
Pfam (PF02373)
In PDB
Homo sapiens (Human)Histone demethylase JARID1A,Jumonji/ARID domain-containing protein 1A,Retinoblastoma-binding protein 2,RBBP-2,Histone demethylase JARID1A,Jumonji/ARID domain-containing protein 1A,Retinoblastoma-binding protein 2,RBBP-2
2A2-OXOGLUTARIC ACIDnon-polymer146.11Chemie (AKG)
3AMANGANESE (II) IONnon-polymer54.91Chemie (MN)
4AGLYCEROLnon-polymer92.14Chemie (GOL)
5waterwater18.0259Chemie (HOH)
Sequence modifications
A: 1 - 347 (UniProt: P29375)
PDBExternal DatabaseDetails
His -1-expression tag
Asn 0-expression tag
A: 348 - 588 (UniProt: P29375)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37944.8
Non-Polymers*Number of molecules6
Total formula weight569.4
All*Total formula weight38514.2
*Water molecules are not included.

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PDB entries from 2024-07-24

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