5IUE
Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, E, G, I) | cDNA FLJ39643 fis, clone SMINT2004023, highly similar to HLA class I histocompatibility antigen, alphachain F | polymer | 284 | 32769.1 | 4 | UniProt (B3KUD8) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P30511) | Homo sapiens (Human) | |
| 2 | B, D, F, H (B, F, H, J) | Beta-2-microglobulin | polymer | 182 | 20060.3 | 4 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | I, J, K, L (K, L, M, N) | Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP | polymer | 8 | 1073.2 | 4 | Trichoplusia ni | ||
| 4 | M (I) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | N, O, P, Q, R... (A, B, E, F, G...) | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence modifications
B, F, H, J: -1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met -68 | - | initiating methionine |
| Leu -67 | - | expression tag |
| Leu -66 | - | expression tag |
| Val -65 | - | expression tag |
| Asn -64 | - | expression tag |
| Gln -63 | - | expression tag |
| Ser -62 | - | expression tag |
| His -61 | - | expression tag |
| Gln -60 | - | expression tag |
| Gly -59 | - | expression tag |
| Phe -58 | - | expression tag |
| Asn -57 | - | expression tag |
| Lys -56 | - | expression tag |
| Glu -55 | - | expression tag |
| His -54 | - | expression tag |
| Thr -53 | - | expression tag |
| Ser -52 | - | expression tag |
| Lys -51 | - | expression tag |
| Met -50 | - | expression tag |
| Val -49 | - | expression tag |
| Ser -48 | - | expression tag |
| Ala -47 | - | expression tag |
| Ile -46 | - | expression tag |
| Val -45 | - | expression tag |
| Leu -44 | - | expression tag |
| Tyr -43 | - | expression tag |
| Val -42 | - | expression tag |
| Leu -41 | - | expression tag |
| Leu -40 | - | expression tag |
| Ala -39 | - | expression tag |
| Ala -38 | - | expression tag |
| Ala -37 | - | expression tag |
| Ala -36 | - | expression tag |
| His -35 | - | expression tag |
| Ser -34 | - | expression tag |
| Ala -33 | - | expression tag |
| Phe -32 | - | expression tag |
| Ala -31 | - | expression tag |
| Ala -30 | - | expression tag |
| Asp -29 | - | expression tag |
| Leu -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Leu -15 | - | expression tag |
| Glu -14 | - | expression tag |
| Val -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Phe -11 | - | expression tag |
| Gln -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Pro -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gly -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Asp -1 | Glu 19 | conflict |
| Pro 0 | Ala 20 | conflict |
| Gly 100 | - | expression tag |
| Gly 101 | - | expression tag |
| Gly 102 | - | expression tag |
| Gly 103 | - | expression tag |
| Ser 104 | - | expression tag |
| Gly 105 | - | expression tag |
| Gly 106 | - | expression tag |
| Ser 107 | - | expression tag |
| Gly 108 | - | expression tag |
| Ser 109 | - | expression tag |
| Gly 110 | - | expression tag |
| Gly 111 | - | expression tag |
| Gly 112 | - | expression tag |
| Ser 113 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 215610.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 215831.5 |
