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5IUE

Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors

Functional Information from GO Data
ChainGOidnamespacecontents
B0006955biological_processimmune response
B0042612cellular_componentMHC class I protein complex
F0006955biological_processimmune response
F0042612cellular_componentMHC class I protein complex
H0006955biological_processimmune response
H0042612cellular_componentMHC class I protein complex
J0006955biological_processimmune response
J0042612cellular_componentMHC class I protein complex
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH
ChainResidueDetails
BTYR78-HIS84
ATYR257-HIS263

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1132
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
AGLY1-ILE284
EGLY1-ILE284
GGLY1-ILE284
IGLY1-ILE284

site_idSWS_FT_FI2
Number of Residues20
DetailsBINDING: BINDING => ECO:0000269|PubMed:28636952
ChainResidueDetails
AASN70
EGLU155
GASN70
GARG84
GTHR143
GTYR147
GGLU155
IASN70
IARG84
ITHR143
ITYR147
AARG84
IGLU155
ATHR143
ATYR147
AGLU155
EASN70
EARG84
ETHR143
ETYR147

site_idSWS_FT_FI3
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000250
ChainResidueDetails
AASN86
FLYS58
FLYS91
FLYS94
HLYS19
HLYS41
HLYS48
HLYS58
HLYS91
HLYS94
JLYS19
EASN86
JLYS41
JLYS48
JLYS58
JLYS91
JLYS94
GASN86
IASN86
BLYS91
BLYS94
FLYS19
FLYS41
FLYS48

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PDB entries from 2024-11-06

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