5ITZ
Crystal structure of the SAC domain of CPAP in a complex with Tubulin and Darpin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 1 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (Bovine) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
2 | B | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB | Bos taurus (Bovine) | |
3 | D | Centromere protein J | polymer | 129 | 14889.8 | 1 | UniProt (Q9HC77) In PDB | Homo sapiens (Human) | CENP-J,Centrosomal P4.1-associated protein,LAG-3-associated protein,LYST-interacting protein 1 |
4 | F | Designed ankyrin repeat protein (DARPIN) D1 | polymer | 127 | 13355.3 | 1 | synthetic construct | ||
5 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
7 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
8 | B | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | non-polymer | 399.4 | 1 | Chemie (LOC) | |||
9 | water | water | 18.0 | 473 | Chemie (HOH) |
Sequence modifications
D: 311 - 422 (UniProt: Q9HC77)
PDB | External Database | Details |
---|---|---|
Met 294 | - | initiating methionine |
Ala 295 | - | expression tag |
His 296 | - | expression tag |
His 297 | - | expression tag |
His 298 | - | expression tag |
His 299 | - | expression tag |
His 300 | - | expression tag |
His 301 | - | expression tag |
Gly 302 | - | expression tag |
Ser 303 | - | expression tag |
Leu 304 | - | expression tag |
Val 305 | - | expression tag |
Pro 306 | - | expression tag |
Arg 307 | - | expression tag |
Gly 308 | - | expression tag |
Ser 309 | - | expression tag |
Ala 310 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 128449.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1390.1 | |
All* | Total formula weight | 129839.5 |