5ITU

Crystal Structure of Human NEIL1(242K) bound to duplex DNA containing THF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Endonuclease 8-like 1	polymer	400	44897.4	3	UniProt (Q96FI4) Pfam (PF01149) Pfam (PF09292) In PDB	Homo sapiens (Human)	DNA glycosylase/AP lyase Neil1,DNA-(apurinic or apyrimidinic site) lyase Neil1,Endonuclease VIII-like 1,FPG1,Nei homolog 1,NEH1,Nei-like protein 1
2	D, F, H	DNA (5'-D(*CP*GP*TP*CP*CP*AP*CP*GP*TP*CP*TP*AP*C)-3')	polymer	13	3887.5	3		unidentified
3	E, G, I	DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3')	polymer	13	4016.6	3		unidentified
4		water	water		18.0	179	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 390 (UniProt: Q96FI4)

PDB	External Database	Details
Ala 391	-	expression tag
Ala 392	-	expression tag
Leu 393	-	expression tag
Gly 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	158404.6
All*	Total formula weight	158404.6

*Water molecules are not included.