5ITU
Crystal Structure of Human NEIL1(242K) bound to duplex DNA containing THF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Endonuclease 8-like 1 | polymer | 400 | 44897.4 | 3 | UniProt (Q96FI4) Pfam (PF01149) Pfam (PF09292) | Homo sapiens (Human) | DNA glycosylase/AP lyase Neil1,DNA-(apurinic or apyrimidinic site) lyase Neil1,Endonuclease VIII-like 1,FPG1,Nei homolog 1,NEH1,Nei-like protein 1 |
| 2 | D, F, H (D, F, H) | DNA (5'-D(*CP*GP*TP*CP*CP*AP*CP*GP*TP*CP*TP*AP*C)-3') | polymer | 13 | 3887.5 | 3 | unidentified | ||
| 3 | E, G, I (E, G, I) | DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3') | polymer | 13 | 4016.6 | 3 | unidentified | ||
| 4 | J, K, L, M, N... (A, B, D, E, F...) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 390 (UniProt: Q96FI4)
| PDB | External Database | Details |
|---|---|---|
| Ala 391 | - | expression tag |
| Ala 392 | - | expression tag |
| Leu 393 | - | expression tag |
| Gly 394 | - | expression tag |
| His 395 | - | expression tag |
| His 396 | - | expression tag |
| His 397 | - | expression tag |
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 158404.6 | |
| All* | Total formula weight | 158404.6 |
