5ISI

Crystal structure of mouse CARM1 in complex with inhibitor SA0920 (5'-amino-5'-deoxyadenosine)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Histone-arginine methyltransferase CARM1	polymer	361	40850.5	4	UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) In PDB	Mus musculus (Mouse)	Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4
2	A, B, C, D	5'-amino-5'-deoxyadenosine	non-polymer		266.3	4	Chemie (5N5)
3	A, B, C, D	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
4	A, C	1,2-DIMETHOXYETHANE	non-polymer		90.1	2	Chemie (DXE)
5		water	water		18.0	15	Chemie (HOH)

Sequence modifications

A, B, C, D: 130 - 487 (UniProt: Q9WVG6)

PDB	External Database	Details
Gly 127	-	expression tag
His 128	-	expression tag
Met 129	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	163401.8
Non-Polymers*	Number of molecules	12
	Total formula weight	1617.7
All*	Total formula weight	165019.5

*Water molecules are not included.