5IS5
Discovery and Pharmacological Characterization of Novel Quinazoline-based PI3K delta-selective Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 1044 | 119999.5 | 1 | UniProt (Q3UDT3) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) UniProt (by SIFTS) (O35904) | Mus musculus (Mouse) | |
| 2 | B (A) | 5-{4-[3-(4-acetylpiperazine-1-carbonyl)phenyl]quinazolin-6-yl}-2-methoxypyridine-3-carbonitrile | non-polymer | 492.5 | 1 | Chemie (6CY) | |||
| 3 | C (A) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 119999.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 492.5 | |
| All* | Total formula weight | 120492.0 |
