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5INN

Mouse Tdp2 D358N protein, apo state with increased disorder amongst variable DNA-binding grasp conformations

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Tyrosyl-DNA phosphodiesterase 2polymer25628904.25UniProt (Q9JJX7)
Pfam (PF03372)
Mus musculus (Mouse)Tyr-DNA phosphodiesterase 2,5'-tyrosyl-DNA phosphodiesterase,5'-Tyr-DNA phosphodiesterase,TRAF and TNF receptor-associated protein
2F, I, K, L
(A, C, D, E)
SULFATE IONnon-polymer96.14Chemie (SO4)
3G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4H, J
(B, C)
CHLORIDE IONnon-polymer35.52Chemie (CL)
5M, N, O, P, Q
(A, B, C, D, E)
waterwater18.0148Chemie (HOH)
Sequence modifications
A, B, C, D, E: 118 - 370 (UniProt: Q9JJX7)
PDBExternal DatabaseDetails
Ser 115-expression tag
Lys 116-expression tag
Gly 117-expression tag
Asn 358Asp 358engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight144521.2
Non-Polymers*Number of molecules7
Total formula weight547.3
All*Total formula weight145068.5
*Water molecules are not included.

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PDB entries from 2025-12-24

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