5IL1
Crystal structure of SAM-bound METTL3-METTL14 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | METTL3 | polymer | 212 | 24427.1 | 1 | UniProt (Q86U44) Pfam (PF05063) | Homo sapiens (Human) | MT-A70,Methyltransferase-like protein 3 |
| 2 | B (B) | METTL14 | polymer | 300 | 34794.4 | 1 | UniProt (Q9HCE5) Pfam (PF05063) | Homo sapiens (Human) | Methyltransferase-like protein 14 |
| 3 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | D, E, F (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59221.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 584.6 | |
| All* | Total formula weight | 59806.2 |
