5IL1
Crystal structure of SAM-bound METTL3-METTL14 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | METTL3 | polymer | 212 | 24427.1 | 1 | UniProt (Q86U44) Pfam (PF05063) | Homo sapiens (Human) | MT-A70,Methyltransferase-like protein 3 |
| 2 | B (B) | METTL14 | polymer | 300 | 34794.4 | 1 | UniProt (Q9HCE5) Pfam (PF05063) | Homo sapiens (Human) | Methyltransferase-like protein 14 |
| 3 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) | |||
| 4 | D, E, F (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59221.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 584.6 | |
| All* | Total formula weight | 59806.2 |
