5IKQ
The Structure of Meclofenamic Acid Bound to Human Cyclooxygenase-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prostaglandin G/H synthase 2 | polymer | 551 | 63425.3 | 2 | UniProt (P35354) Pfam (PF03098) | Homo sapiens (Human) | Cyclooxygenase-2,COX-2,PHS II,Prostaglandin H2 synthase 2,PGHS-2,Prostaglandin-endoperoxide synthase 2 |
| 2 | C, D (C, D) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G04854NQ) | |||
| 3 | E (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 4 | F, L (A, B) | 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid | non-polymer | 296.1 | 2 | Chemie (JMS) | |||
| 5 | G, H, M, N (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | I, K (A, B) | PROTOPORPHYRIN IX CONTAINING CO | non-polymer | 619.6 | 2 | Chemie (COH) | |||
| 7 | J, O, P (A, B) | ACRYLIC ACID | non-polymer | 72.1 | 3 | Chemie (AKR) | |||
| 8 | Q, R (A, B) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126850.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1497.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3224.8 | |
| All* | Total formula weight | 131572.9 |
