5IKC
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, L | MAb 6H10 light chain | polymer | 213 | 23510.0 | 2 | UniProt (A0A0U5BC76) Pfam (PF07686) Pfam (PF07654) In PDB | Mus musculus (Mouse) | |
| 2 | B, H | Ighg protein | polymer | 215 | 22799.2 | 2 | UniProt (Q569X1) Pfam (PF07686) Pfam (PF07654) In PDB | Mus musculus (Mouse) | |
| 3 | M, N | Neuronal migration protein doublecortin | polymer | 90 | 10398.7 | 2 | UniProt (O43602) Pfam (PF03607) In PDB | Homo sapiens (Human) | Doublin,Lissencephalin-X,Lis-X |
| 4 | B, H | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 385 | Chemie (HOH) |
Sequence modifications
A, L: 2 - 213 (UniProt: A0A0U5BC76)
B, H: 2 - 215 (UniProt: Q569X1)
M, N: 52 - 140 (UniProt: O43602)
| PDB | External Database | Details |
|---|---|---|
| Asp 1 | - | expression tag |
| Ser 7 | Thr 27 | conflict |
| Gln 8 | Pro 28 | conflict |
| Leu 10 | Phe 30 | conflict |
| Met 11 | Leu 31 | conflict |
| Ser 12 | Phe 32 | conflict |
| Thr 13 | Val 33 | conflict |
| Val 15 | Ala 35 | conflict |
| Ser 20 | Thr 40 | conflict |
| Thr 22 | Ser 42 | conflict |
| Ile 28 | Arg 48 | conflict |
| Asp 30 | Leu 50 | conflict |
| Thr 31 | Asn 51 | conflict |
| Ala 32 | Asp 52 | conflict |
| Gln 38 | Glu 58 | conflict |
| Pro 46 | Leu 66 | conflict |
| Leu 50 | Tyr 70 | conflict |
| His 55 | Phe 75 | conflict |
| Thr 63 | Ser 83 | conflict |
| Ser 67 | Tyr 87 | conflict |
| Leu 73 | Phe 93 | conflict |
| Asn 76 | Ser 96 | conflict |
| Asn 77 | Thr 97 | conflict |
| Ser 80 | Ala 100 | conflict |
| Asp 81 | Glu 101 | conflict |
| Asp 85 | Val 105 | conflict |
| Leu 89 | Gln 109 | conflict |
| His 91 | Asp 111 | conflict |
| Trp 92 | Tyr 112 | conflict |
| Asn 93 | Arg 113 | conflict |
| Tyr 94 | Ser 114 | conflict |
| Leu 96 | Trp 116 | conflict |
| Ala 100 | Gly 120 | conflict |
| Leu 106 | Ile 126 | conflict |
| Gly 108 | Arg 128 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Pca 1 | - | expression tag |
| Gln 5 | Leu 24 | conflict |
| Ala 9 | Thr 28 | conflict |
| Asp 10 | Glu 29 | conflict |
| Asp 28 | Ser 47 | conflict |
| Asp 32 | Ser 51 | conflict |
| Tyr 33 | Leu 52 | conflict |
| Val 34 | Leu 53 | conflict |
| Lys 38 | Met 57 | conflict |
| Arg 50 | Trp 69 | conflict |
| Ala 54 | Glu 73 | conflict |
| Asn 55 | Asp 74 | conflict |
| Ala 57 | Glu 76 | conflict |
| Ala 61 | Val 80 | conflict |
| Asp 73 | Ala 92 | conflict |
| Glu 89 | Gly 108 | conflict |
| Val 93 | Thr 112 | conflict |
| - | Leu 116 | deletion |
| - | Phe 117 | deletion |
| - | Tyr 118 | deletion |
| - | Gly 119 | deletion |
| - | Tyr 120 | deletion |
| - | Asp 121 | deletion |
| Gly 97 | Asp 122 | conflict |
| Arg 98 | Gly 123 | conflict |
| Ser 99 | Arg 124 | conflict |
| Lys 100 | Asp 125 | conflict |
| Ser 104 | Tyr 129 | conflict |
| Leu 111 | Ile 136 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 51 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 113415.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 113486.7 |
