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5IF0

Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.44 A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, HVRC01cHuGL2 Fab heavy chainpolymer22123614.52Homo sapiens
2B, LVRC01c-HuGL2 Fab light chainpolymer21623816.42Homo sapiens
3G, IGermline-targeting HIV-1 gp120 engineered outer domain eOD-GT8polymer18319889.32Homo sapiens
4G, I2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
5LPHOSPHATE IONnon-polymer95.01Chemie (PO4)
6waterwater18.076Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight134640.5
Non-Polymers*Number of molecules5
Total formula weight979.8
All*Total formula weight135620.3
*Water molecules are not included.

222415

PDB entries from 2024-07-10

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