5IEF
Murine endoplasmic reticulum alpha-glucosidase II with N-butyl-1-deoxynojirimycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neutral alpha-glucosidase AB | polymer | 913 | 103731.9 | 1 | UniProt (Q8BHN3) Pfam (PF13802) Pfam (PF01055) Pfam (PF21365) | Mus musculus (Mouse) | Alpha-glucosidase 2,Glucosidase II subunit alpha |
| 2 | B (B) | Glucosidase 2 subunit beta | polymer | 88 | 9568.3 | 1 | UniProt (O08795) Pfam (PF12999) | Mus musculus (Mouse) | 80K-H protein,Glucosidase II subunit beta,Protein kinase C substrate 60.1 kDa protein heavy chain,PKCSH |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) PubChem (284) | |||
| 5 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 6 | F (A) | (2R,3R,4R,5S)-1-BUTYL-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL | non-polymer | 219.3 | 1 | Chemie (NBV) PubChem (22852327) PubChem (22852328) PubChem (22852329) PubChem (23622616) PubChem (24993292) PubChem (29975291) PubChem (44119800) PubChem (51634) PubChem (45093551) PubChem (46780935) PubChem (70225927) PubChem (70848516) PubChem (71299590) PubChem (71299592) PubChem (71314354) PubChem (501391) PubChem (5150939) PubChem (92338945) PubChem (6098042) PubChem (101433769) PubChem (124490224) PubChem (11816841) PubChem (134694952) PubChem (139024685) PubChem (152961669) PubChem (157352110) PubChem (173225957) PubChem (173729931) PubChem (173729932) PubChem (175474823) PubChem (175759654) | |||
| 7 | G, H (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 2 | Chemie (P6G) PubChem (17472) | |||
| 8 | I, J (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 9 | K, L (A, B) | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A: 33 - 966 (UniProt: Q8BHN3)
| PDB | External Database | Details |
|---|---|---|
| - | Phe 188 | deletion |
| - | Ser 189 | deletion |
| - | Asp 190 | deletion |
| - | Lys 191 | deletion |
| - | Val 192 | deletion |
| - | Ser 193 | deletion |
| - | Leu 194 | deletion |
| - | Ala 195 | deletion |
| - | Leu 196 | deletion |
| - | Gly 197 | deletion |
| - | Ser 198 | deletion |
| - | Val 199 | deletion |
| - | Trp 200 | deletion |
| - | Asp 201 | deletion |
| - | Lys 202 | deletion |
| - | Ile 203 | deletion |
| - | Lys 204 | deletion |
| - | Asn 205 | deletion |
| - | Leu 206 | deletion |
| - | Phe 207 | deletion |
| - | Ser 208 | deletion |
| - | Arg 209 | deletion |
| Ala 967 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 113300.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 969.2 | |
| All* | Total formula weight | 114693.8 |
