5IAW
Novel natural FXR modulator with a unique binding mode
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bile acid receptor | polymer | 228 | 26673.7 | 2 | UniProt (Q96RI1) Pfam (PF00104) | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
| 2 | C, D (C, D) | Peptide from Nuclear receptor coactivator 2 | polymer | 10 | 1220.5 | 2 | UniProt (A0A0B6XJZ8) UniProt (by SIFTS) (Q15596) | Homo sapiens | |
| 3 | E, F, G (A, B) | (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 4-hydroxybenzoate | non-polymer | 274.4 | 3 | Chemie (T73) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55788.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 823.1 | |
| All* | Total formula weight | 56611.3 |
