5I9X
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with bosutinib (SKI-606)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ephrin type-A receptor 2 | polymer | 306 | 34462.8 | 1 | UniProt (P29317) Pfam (PF07714) In PDB | Homo sapiens (Human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
2 | A | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile | non-polymer | 530.4 | 1 | Chemie (DB8) | Homo sapiens (Human) | ||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | Homo sapiens (Human) | ||
4 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A: 596 - 900 (UniProt: P29317)
PDB | External Database | Details |
---|---|---|
Gly 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34462.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 778.7 | |
All* | Total formula weight | 35241.6 |