5I83
Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02773986
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CREB-binding protein | polymer | 118 | 13992.0 | 1 | UniProt (Q92793) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | B (A) | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 3 | C (A) | (4R)-4-methyl-7-[(1R)-1-phenylethoxy]-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one | non-polymer | 296.4 | 1 | Chemie (68Y) | |||
| 4 | D (A) | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence modifications
A: 1082 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Gly 1080 | - | expression tag |
| Ser 1081 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13992.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 354.4 | |
| All* | Total formula weight | 14346.5 |
