5I6Z
X-ray structure of the ts2 human serotonin transporter
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium-dependent serotonin transporter | polymer | 549 | 61781.9 | 1 | UniProt (P31645) Pfam (PF00209) | Homo sapiens (Human) | SERT,5HT transporter,5HTT,Solute carrier family 6 member 4 |
| 2 | B (B) | 8B6 antibody, heavy chain | polymer | 221 | 23688.4 | 1 | Mus musculus | ||
| 3 | C (C) | 8B6 antibody, light chain | polymer | 214 | 23718.2 | 1 | Mus musculus | ||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 76 - 618 (UniProt: P31645)
| PDB | External Database | Details |
|---|---|---|
| Gly 74 | - | cloning artifact |
| Ser 75 | - | cloning artifact |
| Ala 291 | Ile 291 | engineered mutation |
| Ser 439 | Thr 439 | engineered mutation |
| Ala 554 | Cys 554 | engineered mutation |
| Ala 580 | Cys 580 | engineered mutation |
| Leu 619 | - | cloning artifact |
| Val 620 | - | cloning artifact |
| Pro 621 | - | cloning artifact |
| Arg 622 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 109188.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 109409.6 |
