5I50
Structure of OmoMYC bound to double-stranded DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Myc proto-oncogene protein | polymer | 118 | 14036.0 | 2 | UniProt (P01106) Pfam (PF00010) Pfam (PF02344) In PDB | Homo sapiens (Human) | Class E basic helix-loop-helix protein 39,bHLHe39,Proto-oncogene c-Myc,Transcription factor p64 |
2 | C | DNA (5'-D(P*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*CP*TP*AP*CP*AP*C)-3') | polymer | 22 | 6658.3 | 1 | synthetic construct | ||
3 | D | DNA (5'-D(P*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*CP*GP*GP*GP*TP*G)-3') | polymer | 22 | 6849.4 | 1 | synthetic construct |
Sequence modifications
A, B: 3 - 92 (UniProt: P01106)
PDB | External Database | Details |
---|---|---|
Met -25 | - | initiating methionine |
Lys -24 | - | expression tag |
His -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
Pro -17 | - | expression tag |
Met -16 | - | expression tag |
Ser -15 | - | expression tag |
Asp -14 | - | expression tag |
Tyr -13 | - | expression tag |
Asp -12 | - | expression tag |
Ile -11 | - | expression tag |
Pro -10 | - | expression tag |
Thr -9 | - | expression tag |
Thr -8 | - | expression tag |
Glu -7 | - | expression tag |
Asn -6 | - | expression tag |
Leu -5 | - | expression tag |
Tyr -4 | - | expression tag |
Phe -3 | - | expression tag |
Gln -2 | - | expression tag |
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Met 1 | - | expression tag |
Ala 2 | - | expression tag |
Thr 63 | Glu 410 | engineered mutation |
Ile 70 | Glu 417 | engineered mutation |
Gln 76 | Arg 423 | engineered mutation |
Asn 77 | Arg 424 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 41579.8 | |
All* | Total formula weight | 41579.8 |