5I1Q
Second bromodomain of TAF1 bound to a pyrrolopyridone compound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Transcription initiation factor TFIID subunit 1 | polymer | 144 | 16576.6 | 1 | UniProt (P21675) Pfam (PF00439) In PDB | Homo sapiens (Human) | Cell cycle gene 1 protein, TBP-associated factor 250 kDa, p250, Transcription initiation factor TFIID 250 kDa subunit, TAFII250 |
2 | A | 3-[6-(but-3-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl]-N,N-dimethylbenzamide | non-polymer | 335.4 | 1 | Chemie (67C) | |||
3 | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A: 1497 - 1638 (UniProt: P21675)
PDB | External Database | Details |
---|---|---|
Gly 1495 | - | expression tag |
Ser 1496 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 16576.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 335.4 | |
All* | Total formula weight | 16912.0 |