5HZI

Crystal structure of photoinhibitable Intersectin1 containing C450M mutant LOV2 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Intersectin-1,NPH1-1,Intersectin-1	polymer	502	58309.2	2	UniProt (Q15811) UniProt (O49003) Pfam (PF00621) Pfam (PF13426) Pfam (PF16652) In PDB	Homo sapiens (Human)	SH3 domain-containing protein 1A,SH3P17,SH3 domain-containing protein 1A,SH3P17
2	A, B	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	2	Chemie (FMN)
3		water	water		18.0	43	Chemie (HOH)

Sequence modifications

A, B: 1230 - 1308 (UniProt: Q15811)
A, B: 1309 - 1451 (UniProt: O49003)

PDB	External Database	Details
Met 1355	Cys 450	engineered mutation

A, B: 1452 - 1723 (UniProt: Q15811)

PDB	External Database	Details
Leu 1724	-	expression tag
Glu 1725	-	expression tag
His 1726	-	expression tag
His 1727	-	expression tag
His 1728	-	expression tag
His 1729	-	expression tag
His 1730	-	expression tag
His 1731	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	116618.3
Non-Polymers*	Number of molecules	2
	Total formula weight	912.7
All*	Total formula weight	117531.0

*Water molecules are not included.